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3 Layers of COVID-19 Protection: New Vaccines, Prevention Drug, and Tests

Medically reviewed by Elizabeth Cueto, M.D.
Written by Ted Samson
Posted on October 9, 2024

This fall and winter, the Centers for Disease Control and Prevention (CDC) expects the number of people hospitalized with respiratory viruses like COVID-19, RSV, and influenza to be similar to or lower than last year — but still higher than before the pandemic. To help protect against the latest COVID-19 variants, the U.S. Food and Drug Administration (FDA) has approved updated vaccines.

Separately, the Infectious Diseases Society of America (IDSA) is recommending people who are immunocompromised consider taking pemivibart (Pemgarda), a preventive treatment against severe illness from COVID-19. Recent research also suggests that taking the antiviral treatment nirmatrelvir-ritonavir (Paxlovid) during a COVID-19 infection can lower the risk of long COVID for people with weakened immune systems or underlying health conditions.

Finally, free COVID-19 tests are now available to U.S. households.

Updated COVID-19 Vaccines

The updated messenger RNA (mRNA) COVID-19 vaccines from Moderna and Pfizer are designed specifically to target the most recent variants of the virus, including the omicron KP.2 strain. Similarly, the updated Novavax COVID-19 vaccine — which is protein-based — has been updated to target the omicron JN.1 strain. This targeted approach aims to provide better protection against hospitalization or death from COVID-19.

The CDC recommends everyone ages 6 months and older receive an updated COVID-19 vaccine. “It is especially important to get your 2024-2025 COVID-19 vaccine if you are ages 65 and older, are at high risk for severe COVID-19, or have never received a COVID-19 vaccine,” according to the agency.

Additional Protection for Immunocompromised Individuals

In August, the IDSA released guidelines recommending pemivibart for people 12 and older who are moderately to severely immunocompromised and may not respond effectively to vaccines. Granted an emergency use authorization by the FDA in March 2024, pemivibart is taken to help prevent COVID-19 in people who are not currently infected with SARS-CoV-2 (the virus that causes COVID-19) and have not had recent exposure to someone with the virus. It’s given as an IV infusion and works by neutralizing (stopping or weakening) the virus if the person is exposed to it.

For people who are immunocompromised and do catch COVID-19, taking nirmatrelvir-ritonavir may help reduce their risk of long COVID. The FDA approved the drug in 2023 to treat moderate COVID-19 in people at high risk of severe illness. An observational study found that taking nirmatrelvir-ritonavir was linked to a 12 percent lower chance of developing long COVID — primarily for people with a higher risk of severe illness from COVID-19.

Free Tests Available

Finally, the federal government will offer free COVID-19 tests through the mail. Every U.S. household can order four tests at COVIDTests.gov. These tests will detect current COVID-19 variants.

Should You Consider the New COVID-19 Vaccines or Treatments if You Have Lung Cancer?

If you have lung cancer, especially if you’re undergoing treatments like chemotherapy or immunotherapy, your immune system may be compromised. This increases your risk of severe COVID-19. Staying up to date on vaccines is crucial to your safety, and pemivibart may offer extra protection. Additionally, nirmatrelvir-ritonavir could help reduce the risk of severe illness if you contract COVID-19. Talk to your doctor about whether these treatments could be right for you.

However, there’s no one-size-fits-all approach to protecting yourself against COVID-19 if you’re living with lung cancer. It’s important to discuss with your doctor whether the latest vaccines, pemivibart, or Paxlovid could be suitable for you.

Discover what past research has said about COVID-19 vaccines and lung cancer.

Find Your Team

If you have questions about COVID-19 vaccines and lung cancer, you’re not alone. By joining MyLungCancerTeam — the social network for people living with lung cancer and their loved ones — you can connect with thousands of others who understand life with lung cancer.

How have your experiences been with COVID-19 and vaccines? Share your story in the comments, or start a conversation on your Activities page.

References
  1. Respiratory Illnesses Data Channel — Centers for Disease Control and Prevention
  2. FDA Approves and Authorizes Updated mRNA COVID-19 Vaccines To Better Protect Against Currently Circulating Variants — U.S. Food & Drug Administration
  3. Novavax COVID-19 Vaccine, Adjuvanted — U.S. Food & Drug Administration
  4. IDSA Suggests New Preventive COVID-19 Agent — Infectious Diseases Society of America
  5. The Latest Research About Paxlovid: Effectiveness, Access, and Possible Long COVID Benefits — JAMA
  6. COVID-19 Vaccine Basics — Centers for Disease Control and Prevention
  7. Staying Up to Date With COVID-19 Vaccines — Centers for Disease Control and Prevention
  8. Technically Speaking: What Is Pemivibart? — Children’s Hospital of Philadelphia
  9. FDA Authorizes Updated Novavax COVID-19 Vaccine To Better Protect Against Currently Circulating Variants — U.S. Food & Drug Administration
  10. ACIP Recommendations — Centers for Disease Control and Prevention
  11. Underlying Conditions and the Higher Risk for Severe COVID-19 — Centers for Disease Control and Prevention
  12. 2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Management of COVID-19: Anti-SARS-CoV-2 Neutralizing Antibody Pemivibart for Pre-Exposure Prophylaxis — The Infectious Diseases Society of America
  13. Who Can and Cannot Take Paxlovid — NHS
  14. The Interplay of Lung Cancer, COVID-19, and Vaccines — International Journal of Molecular Sciences
  15. Immunogenicity of COVID-19 Vaccines in Lung Cancer Patients — Lung Cancer

Elizabeth Cueto, M.D. graduated from the National Polytechnic Institute in Mexico City. Learn more about her here.
Ted Samson is a copy editor at MyHealthTeam. Learn more about him here.

A MyLungCancerTeam Member

I don't think having a covid vac if you have a tumor in your lung is a good idea. Personally I think it's a terrible combination

October 12
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